Macrophage‐released endogenous CD74 inhibits melanoma cell growth and stimulates apoptosis under IFN‐γ stimulatory conditions by inhibiting the MIF/CD74/AKT survival pathway.[39] Structural analysis using AlphaFold2 revealed that both isoforms possessed MHC class II‐associated invariant chain domains. The gene discussed is CD74; the disease is melanoma.