In 2011, Huang et al[20] reported 2 cases of post-thyroid surgery HBS in hyperthyroidism patients, and suggested that thyroid hormone hyperactivation of osteoclast thyroid hormone receptor in hyperthyroidism was another uncommon cause of post-thyroid surgery HBS, and suggested that low magnesium in the post-thyroid surgery period should be the direct basis of diagnosis of HBS. This evidence concerns the gene TG and hyperthyroidism.