At least in vitro, miR-107 overexpression altered aggressiveness in PCa cells, inhibiting proliferation by the G1/S phase arrest targeting cyclin E1, migration, and tumorsphere formation, but did not affect apoptosis or cell motility, modulating the expressions of genes involved in disease pathophysiology and acting as a tumor suppressor [28,49]. This evidence concerns the gene CCNE1 and posterior cortical atrophy.