The overlapping interacting proteins of ITIH4 were ALB, TG, HSPA1B, PGK1, ACTBL2, ACTG1, VTN, FN1, CXCR4, CXCR5, CCR5, CCL4, SDC3, SCD5, CR2, CD8A, CD4, and CD209, which were found to have a link with RA. Here, CD8A is linked to rheumatoid arthritis.