The overlapping interacting proteins of ITIH4 were ALB, TG, HSPA1B, PGK1, ACTBL2, ACTG1, VTN, FN1, CXCR4, CXCR5, CCR5, CCL4, SDC3, SCD5, CR2, CD8A, CD4, and CD209, which were found to have a link with RA. The gene discussed is FN1; the disease is rheumatoid arthritis.