ACE2 and stroke disorder: Additionally, disturbances in the receptor for Ang-1–7, the Mas receptor, may also be a suppressed target after stroke, which provokes these types of responses when dysregulated, possibly in response to inflammatory cytokines, which may govern the expression of ACE-2, Ang-1–7, the Mas receptor, or other components of this signaling module [42,43,44,45,46].