The patients with COVID-19+ had lower GPx (p = 0.001) and SOD (p = 0.003) activities a lower AGEs (p = 0.007) concentration, a higher TAS (p = 0.017), and greater GR activity (p = 0.000006) and GSTpi (p = 0.00001) and TBARs (p = 0.034) concentrations as compared to those in the group without clinical symptoms. Here, GSR is linked to COVID-19.