PHF8 and acute promyelocytic leukemia: PHF8 overexpression is reported in several kinds of solid and hematologic malignancies, including cancer of the prostate, breast, gastric, liver, lung, and colon, together with acute promyelocytic leukemia (APL) and acute myeloid leukemia (AML) [21,22,23,24,25,26,27,28].