PHF8 overexpression is reported in several kinds of solid and hematologic malignancies, including cancer of the prostate, breast, gastric, liver, lung, and colon, together with acute promyelocytic leukemia (APL) and acute myeloid leukemia (AML) [21,22,23,24,25,26,27,28]. The gene discussed is PHF8; the disease is acute myeloid leukemia.