MDM2 and acute myeloid leukemia: Other genes variants showing strong association to AML were CYP3A4 (A290G) [71], CYP2B6 + CYP3A4 [70], MDM2 T309G + P21 ser31arg [83], XRCC1 [92], VDR FOKI) [90], and NQO1 (C609T) [86].