AML: acute myeloid leukemia; ALL: acute lymphoblastic leukemia; MRD: minimal residual disease; NPM1: nucleophosmin 1; FLT3: Fms-like tyrosine kinase-3; CNS: central nervous system; SCT: Stem cell transplantation; CR: complete remission. This evidence concerns the gene FLT3 and acute myeloid leukemia.