PTH: parathyroid hormone, ALP: alkaline phosphatase, eGFR: estimated glomerular filtration rate, MHD: maintenance hemodialysis, Ca x P: calcium-phosphate product, eGFR: estimated glomerular filtration rate, CKD-MBD: Chronic Kidney Disease - Mineral Bone Disorder. The gene discussed is PTH; the disease is abnormal mineralization disorder.