The analysis of the ESRG expression using the TIMER2.0 database (Figure 1) showed a significant upregulation in breast invasive carcinoma (BRCA), COAD, and LUSC with p<0.001, in addition to bladder urothelial carcinoma (BLCA), lung adenocarcinoma (LUAD), READ, and UCEC with p<0.01. The gene discussed is ESRG; the disease is bladder transitional cell carcinoma.