In patients with COAD and READ, we found a significant negative correlation between the expression of ESRG and the abundance of CD8+ T cells in COAD (Cor = -0.201, p = 4.50E-05) (Figure 7A) and READ (Cor = -0.027, p = 0.001) (Figure 7B). The gene discussed is ESRG; the disease is colon adenocarcinoma.