Comparing our study findings to existing literature there is one study that examined the expression of ESRG in various intracranial malignancies and stated that ESRG was only expressed in embryonal carcinoma and germinoma but barely in the other forms of brain tumors and concluded that the ESRG gene as a sensitive biomarker for these tumors [17]. The gene discussed is ESRG; the disease is brain neoplasm.