Upon inputting co-expressed genes from the TCGA database into MetaCore, numerous pathways and networks were identified as being associated with metabolism, specifically "Chemokines in inflammation in adipose tissues and liver in obesity, type 2 diabetes and metabolic syndrome X", "Immune response_IFN-alpha/beta signaling via JAK/STAT networks". This evidence concerns the gene SOAT1 and obesity due to melanocortin 4 receptor deficiency.