ROBO1 and gastric cancer: Researchers detected coordinated activation of CTTN transcription by STAT3 and NF-κB p100 in AGS and MKN45 cells, which indicated the presence of a multifaceted network driven by CAF-derived SLIT2/ROBO1/NEK9/TRIM28/CTTN/STAT3, suggesting several ways to inhibit the metastasis of GC [117].