Thyroid cells in Hashimoto's thyroiditis organoids maintain properties similar to those of thyroid tissue. The expression of DTWMK gradually decreased in HT organoids, suggesting that DTYMK may be related to the progression of HT to PTC. In addition, the chemokines CCL2 and CCL3 were significantly highly expressed in HT organoids. Here, CCL3 is linked to hematocrit.