tested the observation that therapy-resistant cancer cells undergoing epithelial-mesenchymal transformation (EMT) were more likely to die via induced ferroptosis when compared to nonresistant cancer cells and demonstrated that β-elemene in combination cetuximab induced ferroptotic cell death in KRAS mutant CRC cells (HCT116 and Lovo)23,.50 This evidence concerns the gene KRAS and colorectal carcinoma.