Additionally, compared to normal gastric epithelial cells (GES-1) and colon epithelial cells (NCM460), TRPC5 mRNA and protein levels were markedly elevated in gastric cancer cell lines (MGC-803, BGC-823, MKN-45, AGS) and colorectal cancer cell lines (HCT-116, DLD-1, SW480, SW620) (Figure 1C-1E). Here, TRPC5 is linked to gastric cancer.