Moreover, Ki67 staining revealed that co-transfection with OE-RUNX1 resulted in elevated colorectal cancer cell proliferation, an increase that MUC13 knockdown partially counteracted (Supplementary Figure 6A). Meanwhile, evaluation of TCGA and GTEx datasets via the GEPIA platform revealed a positive association between MUC13 and well-established cell proliferation markers, namely MKI67, MCM2, and PCNA (Supplementary Figure 6B). Here, RUNX1 is linked to colorectal cancer.