We detected the expression of RUNX1 in human normal liver cell line LO-2 and five available hepatocellular carcinoma (HCC) cell lines (Huh7, HepG2, Hep3B, SK-Hep1, and MHCC97-H), and results demonstrated a higher expression of RUNX1 in HCC cell lines, compared with LO-2, in both mRNA and protein levels (Supplementary Figures 2A, B). The gene discussed is RUNX1; the disease is hepatocellular carcinoma.