ABCC2 (also known as multi-drug resistance protein 2, MRP-2) functions as an organic anion pump in the apical epithelium of cells and participates in the transportation of anti-cancer drugs (such as cisplatin, doxorubicin, etoposide, PTX and CBP) across cell surface and intracellular organelle membrane 53-56. The gene discussed is ABCC2; the disease is cancer.