SLC27A4 and diabetic kidney disease: Although FATP2 and FATP4 are both highly expressed in the liver and kidney, they differ in that FATP2 and FATP4 are mainly responsible for the transport of free fatty acids in the tubules in the kidney, and mainly regulate the lipid uptake of proximal renal tubular cells in the high-glucose environment and the activity of fatty acid oxidases to mediate the onset and progression of DKD 16.