In addition, the Univariate Cox regression analysis showed that tumor recurrence (P = 0.001 HR = 3.44 95%CI = 1.667-7.100), M stage (P = 0.011 HR = 2.562 95%CI = 1.238-5.301), clinical stage (P = 0.046 HR = 2.403 95%CI = 1.015-5.692), and the expression of SIX4 (P = 0.017 HR = 2.577 95%CI = 1.180-5.625) were associated with the patient survival. The gene discussed is SIX4; the disease is neoplasm.