Interestingly, the downregulation of 17 proteins linked to protein stabilization, including Ras-related protein Rab-21 (RAB21), flotillin-1 (FLOT1), interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA), RPAP3, desmoglein-1 (DSG1), BAG family molecular chaperone regulator 3 (BAG3), 60S ribosomal protein L5 (RPL5), profilin-2 (PFN2), and FLNA in FGF8-silenced cells, accentuates the role of FGF8 in ovarian cancer progression (Supplementary file 3). The gene discussed is PFN2; the disease is ovarian carcinoma.