To investigate the effect of lncRNA CADM2-AS1 on the metastasis of GC cells, lncRNA CADM2-AS1 was knocked down in HGC-27 and BGC-823 by ASO (HGC-27 ASO-CADM2-AS1 and BGC-823 ASO-CADM2-AS1) (Figure 2A). The gene discussed is CADM2; the disease is gastric cancer.