MMP9 and brain infarction: For cerebral infarction, BBR can effectively reduce blood lipid levels, inhibit the expression of oxidized low-density lipoprotein (ox-LDL) and matrix metalloproteinase-9 (MMP-9), inhibit the growth of carotid atherosclerotic plaque, reduce plaque area, improve plaque stability, and improve the long-term neurological score of cerebral infarction patients (Chai, M. J. et al., 2017a).