TH and Parkinson disease: In the study of Negahdar et al. (Negahdar et al., 2015) by using 6-hydroxydopamine (6-OHDA) -induced PD model, BBR could significantly improve lateral rotation behavior in PD rats, and could also prevent the reduction of the number of tyrosine-hydroxylase (TH) -positive neurons in the group, providing a new strategy for PD treatment.