Nonsense and missense germline mutations within the T‐box DNA‐binding domain of human TBX20 are associated with a family history of CHD and a diverse array of developmental anomalies, with loss‐of‐function studies of TBX20 indicating reduced cardiomyocyte proliferation and cell cycle arrest during heart development.79, 80. The gene discussed is TBX20; the disease is coronary artery disorder.