Causal P and LP variants were identified in 5 out of 13 patients with a history of cryptorchidism (three in FGFR1, one in ARHGAP5, and one in GNRH1), in 2 out of 8 patients with hearing impairment (CHD7 and FGFR1 genes), and in 2 out of 2 patients with renal agenesis (ANOS1 gene) (Supplementary Table S3). This evidence concerns the gene GNRH1 and cryptorchidism.