As illustrated in Figure 1A, compared with normal group, ADRA2C mRNA expression level was higher in cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), liver hepatocellular carcinoma (LIHC), rectum adenocarcinoma (READ) and thyroid carcinoma (THCA). The gene discussed is ADRA2C; the disease is head and neck squamous cell carcinoma.