KM survival analysis confirmed that a high ADRA2C mRNA level was associated with a favorable prognosis in GBMLGG and UVM, while a high ADRA2C expression level was correlated with a poor prognosis in ACC, suggesting that ADRA2C may be a protective factor in GBMLGG and UVM patients, as well as being a risk factor for ACC. The gene discussed is ADRA2C; the disease is adrenal cortex carcinoma.