Brf1 expression had clinical prognostic value for T stage (Fig. S1B), pathologic stage (Fig. S1C), AFP level (Fig. S1D, Table 2b), OS (Fig. S1E), Ishak fibrosis score (Table 2) and histologic grade (Fig. S1F) but not for N stage, M stage, pathologic grade, sex, race, age, weight, height, BMI, residual tumor status, adjacent hepatic tissue inflammation status, albumin level, prothrombin time, Child-Pugh score, Ishak fibrosis score, vascular invasion status, DSS, or PFI (Table 2). The gene discussed is BRF1; the disease is neoplasm.