MTF1 and rectum adenocarcinoma: According to the results, patients with a higher expression of MTF1 had a shorter OS in LGG (hazard ratio (HR) = 1.85, P = 0.001) and a longer OS in HNSC (HR = 0.75, P = 0.04), KIRC (HR = 0.59, P = 0.001), and rectum adenocarcinoma (READ) (HR = 0.42, P = 0.045) (Fig. 3A, Supplementary Fig. S2A).