Visualization of molecular docking analysis between daphnoretin and the PI3K/AKT pathway (Fig. 7G) underscored a robust binding affinity, suggesting daphnoretin's potential to target PI3K/AKT-related pathways involved in cell apoptosis and GBM attenuation, as indicated by network pharmacology and docking analyses. The gene discussed is AKT1; the disease is glioblastoma.