STK11 and non-small cell lung carcinoma: Intriguingly, a previous study found that nucleotide metabolites in Lkb1-null cells, including hypoxanthine nucleotide (IMP), AMP, guanosine monophosphate (GMP), dGMP, uridine monophosphate (UMP), ADP, UDP, CDP, dCDP, and deoxythymidine diphosphate (dTDP), were present at consistently lower levels compared with Lkb1-wt cells [27], implying the upregulation of these monophosphate or diphosphate nucleotide metabolites may reinvigorate the immune response against STK11 mutant NSCLC.