CTLs, cytotoxic T‐cells lymphocytes; DCs, dendritic cells; ECM, extra cellular matrix; IFN‐γ, interferon‐γ; IL‐2, interleukin‐2; NK, natural killer cells; ROS, reactive oxygen species; TAMS, tumour associated macrophages, cells; Th‐1, T‐helper cell 1. The gene discussed is IFNG; the disease is neoplasm.