TRPS1 and malignant colon neoplasm: A prior study demonstrated that TRPS1 expression is elevated in colon cancer and that high TRPS1 levels are significantly correlated with positive lymph node metastasis and more advanced pathological stages in colon cancer patients.10 Information is scarce regarding the identification of TRPS1 mutations or the elucidation of TRPS1’s mechanism in colon cancer.