As is well known, EMT is a process in which epithelial cells transdifferentiate into mesenchymal cells, enhancing their motility and developing an invasive phenotype in the CRC developmental stage.7 During the EMT process, epithelial markers like E-cadherin, ZO-1, and occludin are downregulated, while mesenchymal markers such as fibronectin, vimentin, and N-cadherin are upregulated. This evidence concerns the gene CDH1 and colorectal carcinoma.