CD4 and celiac disease: It contains native and deamidated peptides, 1013 peptides (in the 2018 version) with average length 16 ± 4 amino acids that are reported to stimulate CD4+ T cells with a proliferation with greater than a 2-fold stimulatory index or release of IFN-gamma, or have been shown to give toxic reactions in the intestines of patients with coeliac disease (9 peptides) (Amnuaycheewa et al., 2022).