CD274 and gastric cancer: Previous studies have shown varying co-expression rates among relevant biomarkers.13,17,28 We found that CLDN18.2 positivity was significantly higher in EBV-associated GC (71.9%), which is consistent with the results of several previous studies.13,17 CLDN18.2 positivity was significantly correlated with PD-L1 expression between 37% and 40% regardless of CPS cutoffs (CPS ≥ 1,≥5, and ≥10).