IFNG and systemic lupus erythematosus: Reported cellular immune response rates in adult patients with SLE varied between 36% and 53%, while rates in paediatric patients ranged from 68% to 94%.4 6 7 14 These studies have not identified clear associations with low cellular immune response but have shown a positive correlation between humoral (anti-SARS-CoV-2 Ab and nAb) and cellular (IGRA titres) immune responses.6 7 In a study evaluating adoSLE, where cellular immunity was measured using interferon gamma ELISA (ELISpot), the high immunosuppressive group had a lower cellular immune response than the low immunosuppressive group.14