ABCA8 and gastric cancer: (31) identified three specific GC subtypes—proximal, diffuse, and distal—characterized by unique gene expression profiles, with a notable distinction in ABCA8 expression between diffuse and distal nondiffuse gastric cancers Our study further refined this understanding, revealing that ABCA8 expressing fibroblasts were predominantly found in PCC-NOS tissue, a category of diffuse GC.