The expression of nine genes (TSC22D1, SNCA, SH3YL1, KCNA3, RNF135, TM6SF1, PRDM2, BVES and AMN) was reduced (Fig. 4B), while that of eight genes (VASH2, MAFA, LRRC10B, PIK3R3, TRIL, CELSR3, IDUA and SEPT9) was increased (Fig. 4C) in HCC compared to control livers. This evidence concerns the gene SNCA and hepatocellular carcinoma.