The expression of nine genes (TSC22D1, SNCA, SH3YL1, KCNA3, RNF135, TM6SF1, PRDM2, BVES and AMN) was reduced (Fig. 4B), while that of eight genes (VASH2, MAFA, LRRC10B, PIK3R3, TRIL, CELSR3, IDUA and SEPT9) was increased (Fig. 4C) in HCC compared to control livers. Here, TSC22D1 is linked to hepatocellular carcinoma.