Furthermore, when gavaged weekly, a murine isolate of Akkermansia induced colitis in IL10-/- mice.110 However, in a different model of experimental colitis induced by Dextran Sulfate Sodium (DSS), repeated gavages with various Akkermansia strains, including the mouse strain “139”,111 MucT,42,111,112 and another murine isolate of A. muciniphila113 were all protective. Here, IL10 is linked to colitis.