Zyxin knockout similarly compromised the growth of syngeneic MC38 colon adenocarcinoma (Fig. EV6E–G), where the CD11b+ myeloid cells contained a high proportion of visible phospho-Zyxin labeling, while Sting−/− mice showed a decreased proportion of CD11b+pZyxin+ cells (Fig. EV6H,I). This evidence concerns the gene ITGAM and colon adenocarcinoma.