Gene transcripts encoding ion channels and receptors with high neural specificity included the calcium signaling modulator SIGMAR1 and cannabinoid receptor CNR1. Both had considerably lower patient specificity than oncogenic RTKs EGFR and PDGFRA, despite similar detection levels (Fig. 3c and Supplementary Table 3), highlighting consistent pan-patient expression of NAD targets in glioblastoma. The gene discussed is SIGMAR1; the disease is glioblastoma.