Conversely, downregulated AP-1 factors included ATF5 and ATF6B, shown to promote glioblastoma cell survival and radioresistance, respectively47,48, whereas FOSL1, implicated in response to irradiation in glioblastoma, showed no upregulation49 (Extended Data Fig. 6e). The gene discussed is FOSL1; the disease is glioblastoma.