OAS1 and neoplasm: We observed that knockout of OAS1 or IFIT3 could increase tumor volume (Fig. S8J), exosome content (Fig. 7G), and mRNA stability of RAB5A, RAB7, and RAB11A (Figs. 7H and S8, K and L), and combined knockout of OAS1 and IFIT3 further enhanced the above effects (Figs. 7, F–H and S8, J–L).