To determine whether Treg-specific expression of Sf3b1-K700E affects cancer development, we compared the growth of AML (acute myeloid leukemia) in Foxp3YFP-Cre and Sf3b1K700Efl/+/Foxp3YFP-Cre mice (fig. This evidence concerns the gene SF3B1 and acute myeloid leukemia.