For example, the T1D SNP rs3024505 (p=0.200) connected to the promoters of IL9 and FAIM3 (Figure 8—figure supplement 1B) and the celiac SNP rs13010713 (p=0.154) contacting the ITGA4 promoter (Figure 8—figure supplement 1C) are predicted to disrupt binding sites for MZF1 (Figure 8—figure supplement 1D) and SOX4 (Figure 8—figure supplement 1E). The gene discussed is MZF1; the disease is type 1 diabetes mellitus.