TRPV1 and neoplasm: We tested whether this was the case using western blotting and discovered an overexpression of the sigma 1 receptor (σ1R) and increased TRPV1 phosphorylation in the TGM ganglia from tumor-bearing animals (Figure 2G, Figure 2—source data 1, Figure 2—source data 2, Figure 2—source data 3, Figure 2H and I).