Individuals with information on PrEP use were more often diagnosed with a recent HIV infection and had a higher CD4+ T-cell count (median: 435 cells/mm3, interquartile range (IQR): 251–619) at the time of diagnosis than individuals without information on PrEP (median: 390 cells/mm3, IQR: 201–580). Here, CD4 is linked to HIV infectious disease.