LGI1 and epilepsy: The expression of LGI1 has been well characterized within the brain,41,42 given its association with the development of epilepsy and limbic encephalitis.17,18 Studies on its expression within the peripheral nervous system are lacking, despite the known presence of other members of the LGI family.32 Single-cell RNA-Seq of the mouse nervous system, however, indicates LGI1 expression in DRG neurons, in particular nociceptors.43 In line with this, using ISH we found LGI1 mRNA to be highly expressed in mouse DRG, albeit in both nociceptive and non-nociceptive neuron populations.