PPARGC1A and type 2 diabetes nephropathy: In KKAy mice, which is an ideal animal model for early-to-mid-stage type 2 diabetic nephropathy, Mor normalized renal lipid metabolism by improving podocyte cholesterol efflux and regulating podocyte cholesterol uptake through upregulating the PGC-1α/LXRs/ABCA1 and PGC-1α/PPARγ/CD36 signaling pathways, respectively.