The key factors are as follows: clinical factors—male sex, high body mass index, and complex comorbidity; imaging factors—multivessel coronary lesions and LV lateral wall involvement; genetic factors—minor allelic variants of VEGFR-2 rs2305948; and treatment factors—PCI only for the infarct-related coronary artery instead of CABG in cases of multivessel coronary artery disease, and low-intensity statin dosage. This evidence concerns the gene KDR and coronary artery disorder.