While the inheritance pattern of hEDS is autosomal dominant, there is no clear genetic etiology that has been identified, though recent data have provided some candidate mutations, including the MIA3 gene encoding a transport protein essential in collagen synthesis, which was abnormal in 13/100 patients with HDS in one series, and the ELN gene encoding for elastin (13, 14). The gene discussed is ELN; the disease is Ehlers-Danlos syndrome, hypermobility type.