Peritoneal angiogenesis can be alleviated by the Smad7 gene, which reduces capillary vessel density and inhibits the production of VEGF (Zhou et al., 2016), decreasing the activation of p38 and nuclear factor-κB (NF-κB), indicating its powerful role in inhibiting neovascularization in the PF (Silva et al., 2019). Here, NFKB1 is linked to pemphigus foliaceus.